Early Discovery Services

• Routine molecular biology (de novo gene synthesis, cloning, sequencing, etc.)
• Protein expression, purification and characterization (E.coli, baculovirus and mammalian expression, scale up and large scale protein production and purification)
• Peptide synthesis (all modifications, tags, scale-up)
• Enzymology (substrate identification, assay development, optimization and miniaturization for HTS, stability studies, etc.)
• Membrane preparation, binding assays
• Custom cell lines development (high expressers, mass transfectants, clonal selection, cell line characterization and maintenance, etc.)
• Cell-based assays (reporter assays, limited GPCRs, proliferation, cytotoxicity, etc.)
• Selectivity profiling